Lim Group
Welcome to the website of Dr Chun Shen Lim’s computational genomics group. We aim to delineate molecular factors that control gene expression using high-throughput techniques and computational pipelines we develop. Our goal is to address health issues and infectious diseases, e.g., hepatitis B virus infection.
news
| Apr 13, 2025 | Our paper on combining long- and short-read sequencing to detect novel translational events has been published  |
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| Feb 27, 2025 | Congratulations Anh on winning the RNA Society Research Presentation Fellowship  |
| Dec 01, 2023 | Congratulations Gabrielle on her well-deserved PhD scholarship!   |
| Sep 25, 2023 | Gabrielle won the travel award from the Molecular Biosystems Fellows Program and attended the conference in Puerto Varas, Chile. Well done!  |
| May 25, 2023 | We have successfully secured a HRC Explorer Grant  |
selected publications
- The exon–intron gene structure upstream of the initiation codon predicts translation efficiencyNucleic Acids Research, 2018
- Solubility-Weighted Index: fast and accurate prediction of protein solubilityBioinformatics, 2020
- Quantitative analysis of the splice variants expressed by the major hepatitis B virus genotypesMicrobial Genomics, 2021
- Analysis of 11,430 recombinant protein production experiments reveals that protein yield is tunable by synonymous codon changes of translation initiation sitesPLOS Computational Biology, 2021
- TISIGNER.com: web services for improving recombinant protein productionNucleic Acids Research, 2021
- Analysis of fungal genomes reveals commonalities of intron gain or loss and functions in intron-poor speciesMolecular Biology and Evolution, 2021
